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Clinical Evidence

Evidence for Care Between Visits

Clinical evidence, case studies, and operational results demonstrating how structured care delivery can improve execution between specialty visits.

Clinical and Operational Results

Heart failure care executed at scale

In a real-world evaluation across community cardiology practices, ISHI demonstrated that structured virtual care workflows can support high-volume intervention without increasing cardiologist burden.

747Heart failure patients included in the evaluation
2,013Clinical alerts managed through structured workflows
99%Clinical alerts addressed within 48 hours
15.5%Improvement in beta-blocker utilization
0%Escalated to community cardiologists
What the Evidence Shows

From visibility to execution

Remote monitoring, virtual care, and care management programs can improve access to information. The evidence focus for ISHI is whether care plans are consistently acted on between visits.

Therapy Optimization

Improved GDMT utilization

Protocol-driven care drove measurable improvement across all four GDMT classes: beta-blockers, ACEI/ARB/ARNI, SGLT2 inhibitors, and MRA.

Clinical Responsiveness

Rapid alert management

Clinical alerts were managed at volume, with 99% addressed within 48 hours through structured escalation pathways.

Operational Viability

No added cardiologist burden

The majority of alerts were handled by the multidisciplinary team, with no escalation required to community cardiologists in the evaluation.

Clinical Evidence Resources

Available resources

Use these resources to understand the clinical rationale, care delivery model, and real-world outcomes behind ISHI’s approach to active management between visits.

Clinical EvidenceCase Study

Executing Heart Failure Care Between Visits

Review real-world outcomes from 747 heart failure patients supported through ISHI's protocol-driven care model.

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Clinical EvidenceEvidence Brief

Transforming Heart Failure Care Through Active Clinical Management Between Visits

Explore the clinical problem, the care model, and the operational framework behind active management between visits.

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Additional Resources

Explore the Resource Center

Browse ASM education, clinical evidence, case studies, and insights from the complete ISHI Resource Center.

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Evidence in context

Clinical evidence is one part of the broader ISHI Resource Center. Explore the ASM framework and insights that explain why execution between visits matters.

Ready to Review the Evidence?

Start with the Clinical Evidence Brief or review the heart failure case study to see how structured care delivery can support execution between visits.

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